Which type of propellant is used for water based aerosols and topical use?

Which type of propellant is used for water based aerosols and topical use?

2. Hydrocarbons :- It can be used for water aerosols and topical use. Example propane (propellant A-108), Butane (propellant A-17).

What are topical aerosols?

Topical aerosols deliver the active drug in the form of a powder, a wet spray, a stream of liquid, or an ointment like product. Vaginal and rectal foams are available that contain estrogens, contraceptives, and anti-inflammation agents.

What is pharmaceutical propellant?

Propellants provide the necessary pressure to discharge the product from the container in the desired form and may also serve as a solvent or dispersion medium for the active ingredients and excipients.

What are the disadvantages of aerosols?

The potential for tracheobronchial irritation, bronchospasm, contamination, and infection of the airway. The common hazards of aerosol therapy are: Airway obstruction ‑ Dehydrated secretions in the patient’s airways may absorb water delivered via aerosol and swell up large enough to obstruct airways.

What are the advantages of aerosols?

The benefits of aerosol treatment include the following:

  • Direct delivery to the treatment site.
  • Faster onset of action than oral medication.
  • Lower requirement of dosage than systemic administration.
  • Reduced systemic adverse effects.

Which is not use as a propellant in aerosol?

Compressed Gases Gases such as nitrogen, nitrous oxide, and carbon dioxide have been used as aerosol propellants for products dispensed as fine mists, foams, or semisolids. But unlike aerosols prepared with liquefied gas propellants, there is no propellant reservoir.

What kind of gas is in an aerosol can?

Aerosol food products generally use nitrous oxide or carbon dioxide as the propellant, while other substances (pharmaceuticals, paints and cosmetics) use flammable hydrocarbons. Cans.

What is the benefit of using aerosol therapy?

Aerosol therapy has several advantages, including direct delivery of drug to the site of action, rapid onset of action, lower dose required than with systemic administration to produce desired clinical outcomes, and minimum systemic adverse effects.

What is the use of inhalation aerosol?

GENERIC NAME: BRONCHODILATOR – AEROSOL ORAL INHALER. USES: This drug relaxes the smooth muscle in the lungs and dilates airways to improve breathing. It is used in the treatment of asthma, chronic bronchitis, and emphysema. The inhaler enables the drug to reach deep into the lungs for maximum benefit.

What are the harmful effects of aerosol spray?

For those repeatedly exposed, however, adverse health effects can include depression of the central nervous and even permanent damage, as well as irritation of the eyes and lungs, and damage to the skin, liver and kidneys.

Is Deodorant an aerosol?

Spray deodorant comes in an aerosol can. The product is applied by spraying it on the skin.

What are some examples of aerosol cans?

If a can is designed to spray out its contents, it is an aerosol can. Examples include spray paint, hair spray, room deodorizers, and many more.

Why are hydrocarbon propellants used in topical aerosols?

Vitthal S. Kulkarni Ph.D., Charles Shaw Ph.D., in Essential Chemistry for Formulators of Semisolid and Liquid Dosages, 2016 Hydrocarbon propellants are used in topical pharmaceutical aerosols because of their environmental acceptance, low toxicity, and lack of reactivity.

How are aerosols different from other type of packaging?

Aerosols are only different type of packaging i.e they are pressurised dosage forms containing one or more active ingredients (product concentrate + propellant) which upon actuation emit a fine dispersion of product concentrate in a gaseous medium. This is where a propellant comes into action.

What are the different types of propellants used in medicine?

Types of propellants commonly used in pharmaceutical aerosols include chlorofluorocarbons, fluorocarbons (trichloromonofluoromethane, dichlorodifluoromethane), hydrocarbons (propane, butane, isobutane), hydrochlorofluorocarbons and hydrofluorocarbons, inert gases (nitrogen, NO2, CO 2) and compressed gases (Alston et al., 2013).

What kind of propellant is used in asthma inhalers?

Propellants 22, 142b, and 152a are used in topical pharmaceuticals. These three propellants have good miscibility with water, which makes them more useful as solvents compared to some other propellants. Medicinal aerosols such as asthma inhalers use the HFC propellants 134a, 227, or a combination of the two.