Where does ocular melanoma metastasize to?
Where does ocular melanoma metastasize to?
The liver is the most common site of metastasis in ocular melanoma. Among those who develop metastatic disease, 90% of patients develop liver disease. However, ocular melanoma can spread to any organ in the body. After the liver, common sites include the lung, bones and brain.
What is life expectancy for ocular melanoma?
5-year relative survival rates for eye melanoma
| SEER stage | 5-year relative survival rate |
|---|---|
| Localized | 84% |
| Regional | 70% |
| Distant | 18% |
| All SEER stages combined | 81% |
Does ocular melanoma always spread?
Some estimates suggest that in 40-50% of individuals, an ocular melanoma will metastasize. Based on the aggressiveness of the particular tumor, as defined by clinical and genetic features, metastasis may be detected as early as 2-3 after diagnosis and rarely as late as decades after treatment.
Can eye melanoma spread to the brain?
Metastasis of the ocular malignant melanoma to the brain is extremely rare and most often occurs simultaneously with liver metastases. Lorigan et al., in clinical and radiological studies, found a total of five cases of brain metastases in 110 cases of metastatic choroidal melanoma [3].
Can ocular melanoma spread brain?
Is ocular melanoma a terminal?
However, it can occur in all races and at any age. Called “OM” for short, ocular melanoma is a malignant tumor that can grow and spread to other parts of the body – this process, known as metastasis, is often fatal and occurs in about half of all cases.
Can you survive ocular melanoma?
The 5-year survival rate for eye melanoma is 82%. When melanoma does not spread outside the eye, the 5-year relative survival rate is about 85%. The 5-year survival rate for those with disease that has spread to surrounding tissues or organs and/or the regional lymph nodes is 71%.
What are the signs that melanoma has spread to the brain?
When melanoma spreads to the brain and symptoms occur, they may include:
- Headaches.
- Seizures.
- Paralysis on one side of your body.
- Problems with your eyesight.
Where does melanoma most often metastasize?
Metastatic melanoma most often spreads to the lymph nodes, brain, bones, liver or lungs, and the additional symptoms experienced at this late stage will depend on where the melanoma has spread.