What is metabolic bone disease?

What is metabolic bone disease?

The common metabolic bone diseases (MBD) include osteoporosis, rickets/ osteomalacia, flurosis and primary hyperparathyroidism (PHPT), while the rare MBDs include Paget’s disease, tumor induced osteomalacia, fibrous dysplasia, osteogenesis imperfecta and so on.

What are the symptoms of metabolic bone disease?

Typical symptoms of metabolic bone disease include:

  • Limping.
  • Bowed legs.
  • Hard lumps along the legs, spinal column, or jaw.
  • Softening and unusual flexibility of the lower jaw.
  • Difficulty raising the body off the ground.
  • Decreased appetite.

What can metabolic bone disease cause?

Osteoporosis is called a “silent disease,” because a majority of patients are unaware of their condition until they develop a bone fracture. Metabolic bone disease in children can result in linear growth reduction, bone deformities, non-traumatic fractures, and impairment of motor development and function.

How do you treat metabolic bone disease?

Treatment and Prognosis Fortunately, if detected early enough, MBD can often be corrected and reversed through making changes and improvements to the husbandry of the animal by providing the needed or adequate levels of UV-A and UV-B lighting and heating, proper supplementation, and other nutrients.

What is the best doctor to see for osteoporosis?

Rheumatologists treat patients with age-related bone diseases. They can diagnose and treat osteoporosis. Endocrinologists, who see patients with hormone-related issues, also manage the treatment of metabolic disorders such as osteoporosis. Orthopedic surgeons may fix fractures.

Is a chronic metabolic bone disease that affects bone formation?

Osteoporosis, the most common metabolic bone disease, affects 200 million persons worldwide. Approximately 28 million Americans have osteoporosis or are at risk for it.

Is metabolic bone disease treatable?

Without treatment, patients with MBD rarely survive. If treatment is given in a timely manner and the apporpriate husbandry changes are made and maintained, the prognosis for patients with mild MBD is very good .

Can certain medications cause metabolic bone disease?

Many drugs can affect bone metabolism. As an example, heparin, warfarin, cyclosporine, glucocorticoids, medroxyprogesterone acetate, cancer drugs, and thyroid hormone can cause bone loss, while thiazide diuretics can minimize bone loss [1,2].

What does metabolic bone disease mean?

Metabolic bone disease is an abnormality of bones caused by a broad spectrum of disorders. Most commonly these disorders are caused by abnormalities of minerals such as calcium, phosphorus, magnesium or vitamin D leading to dramatic clinical disorders that are commonly reversible once the underlying defect has been treated.

What is metabolic bone disease (MBD)?

Metabolic bone disease or MBD refers to a large spectrum of bone disorders, usually caused by mineral abnormalities such as calcium, phosphorus, magnesium or vitamin D. The most common metabolic bone diseases include osteoporosis, osteomalacia, rickets, renal osteodystrophy and osteitis deformans (Paget’s disease of bone).

What are examples of metabolic disorders?

Some examples of metabolic disorders include cystic fibrosis, phenylketonuria (PKU), hyperlipidemia, gout, and rickets.

Is osteoporosis a metabolic bone disease?

Osteoporosis is a metabolic bone disorder that results in fragile bones, bone fractures and bone deformities. Osteoporosis means “porous bone”. It is a metabolic bone disease that results from decreased bone formation, increased bone loss, or both and leads to weak and fragile bones.