What is a high grade astrocytoma?

What is a high grade astrocytoma?

High-grade astrocytomas are either grade 3 or grade 4 brain tumors. Both are malignant, but grade 4 tumors are more aggressive than grade 3 tumors. These tumors most often occur in the cerebral hemispheres but can also occur in the thalamus or, less commonly, in the posterior fossa.

What type of cancer is high grade glioma?

High grade gliomas are malignant (cancerous) tumours that develop from brain cells called astrocytes.

What is the treatment for high grade glioma?

Treatment of a high-grade glioma includes measures to relieve symptoms and eliminate or control the tumor. This may include surgery, radiation, and/or chemotherapy.

What is a high grade primary tumor?

High-grade gliomas are tumors of the glial cells, cells found in the brain and spinal cord. They are called “high-grade” because the tumors are fast-growing and they spread quickly through brain tissue, which makes them hard to treat.

How common is high grade glioma?

High-grade gliomas are rare, with only 360 to 400 new cases occurring each year in North America. They occur equally in boys and girls. High-grade gliomas are classified by their location and by how they appear when examined under a microscope.

How long can you live with a high grade glioma?

The median survival of patients with LGG ranges from 6 to more than 15 years,, especially when there is a favorable genetic profile. In contrast, the median survival for patients with glioblastoma (the most frequent and malignant HGG) is only 15 months.

What stage is a high grade glioma?

High grade gliomas are either World Health Organization (WHO) grade 3 tumours or grade 4. Grade 3 and 4 tumours tend to grow rapidly and spread faster than tumours of a lower grade. The most common grade 3 tumour is anaplastic astrocytoma and the most common grade 4 tumour is glioblastoma multiforme.

How are low grade astrocytomas different from malignant tumors?

Generally, low grade astrocytomas tend to be of bigger size before they become symptomatic, as compared to more aggressive, higher grade astrocytomas. This is because lower grade tumors tend to displace the brain rather than destroying it, and also because they are associated with less brain swelling than malignant ones.

Which is the most aggressive type of astrocytoma?

Astrocytoma can be a slow-growing tumor, or it can be an aggressive cancer that grows quickly. The aggressiveness (grade) of your astrocytoma determines your prognosis and treatment options. Tests and procedures used to diagnose astrocytoma include:

What are the signs and symptoms of astrocytoma?

Astrocytoma signs and symptoms depend on the location of your tumor. Astrocytomas that occur in the brain can cause seizures, headaches and nausea. Astrocytomas that occur in the spinal cord can cause weakness and disability in the area affected by the growing tumor.

Which is the best way to treat astrocytoma tumors?

If feasible, Grade I tumors are best treated with surgical removal, which can be curative in some instances. Grade II tumors are also removed with surgery. However, surgery may involve parts of the brain that are essential for important functions, such as speech or moving the arms and legs.