What class of drug is Dichlorphenamide?
This medication is used to treat a certain inherited condition that causes attacks of muscle weakness or loss of muscle movement that come and go (primary periodic paralysis). Dichlorphenamide belongs to a class of drugs known as carbonic anhydrase inhibitors.
What is keyevis?
KEVEYIS is an oral carbonic anhydrase inhibitor indicated for the treatment. of primary hyperkalemic periodic paralysis, primary hypokalemic periodic. paralysis, and related variants (1)
Who makes KEVEYIS?
Dive Brief: Israel-based Taro Pharmaceuticals will distribute its rare disease drug Keveyis free of charge, after negligible sales and difficulty identifying patients.
What is periodic paralysis?
Periodic paralysis (PP) is a rare genetic disorder. It causes sudden attacks of short-term muscle weakness, stiffness, or paralysis. These attacks may affect the whole body or just 1 or 2 limbs. There are several different forms of PP. They all involve defects in ion channels.
What is Hypokalemic periodic paralysis?
Hypokalemic periodic paralysis is a condition that causes episodes of extreme muscle weakness typically beginning in childhood or adolescence. Most often, these episodes involve a temporary inability to move muscles in the arms and legs. Attacks cause severe weakness or paralysis that usually lasts from hours to days.
What is the trade name for Methazolamide?
BRAND NAME(S): Neptazane. USES: This medication is used in combination with other medications to treat high pressure inside the eye due to certain types of glaucoma. Lowering high pressure inside the eye helps to prevent blindness, vision loss, and nerve damage.
What is Keveyis used for?
How many types of periodic paralysis are there?
There are about seven to eight types of periodic paralysis syndromes, for example, hyperkalemic periodic paralysis or hyperPP and normokalemic periodic paralysis. Signs and symptoms of this syndrome involve episodic muscle weakness.
Is Hypokalemic periodic paralysis rare?
Although its exact prevalence is unknown, hypokalemic periodic paralysis is estimated to affect 1 in 100,000 people. Men tend to experience symptoms of this condition more often than women.
Why Methazolamide is not used?
Methazolamide is rarely used as a diuretic any longer. More potent and effective diuretic drugs are available, such as the loop diuretics (furosemide). Methazolamide, like other carbonic anhydrase inhibitors, is used primarily to lower intraocular pressure in animals with glaucoma.
Which is the best brand of dichlorphenamide to take?
The Daranide brand of dichlorphenamide is used to treat glaucoma. The Keveyis brand of dichlorphenamide is used to treat occasional paralysis (loss of movement) caused by high or low levels of potassium in your blood.
Are there any side effects to taking dichlorphenamide?
Written by Cerner Multum. What is dichlorphenamide? Dichlorphenamide is used to treat occasional paralysis (loss of movement) caused by high or low levels of potassium in your blood. Dichlorphenamide may also be used for purposes not listed in this medication guide.
How often can I take dichlorphenamide for paralysis?
Dosing: Adult. Primary periodic paralysis: Oral: Initial: 50 mg twice daily; may increase or decrease dosage at weekly intervals (or more frequently in response to adverse reactions); maximum: 200 mg/day. Evaluate response and need for continued therapy after 2 months of treatment.
Is it safe to take dichlorphenamide with aspirin?
You should not use dichlorphenamide if you are allergic to it, or if you have: if you also take aspirin in high doses. an electrolyte imbalance (such as low levels of potassium or magnesium in your blood). Avoid using dichlorphenamide if you are pregnant.