Is gestational trophoblastic disease curable?
Gestational Trophoblastic Disease treatment and recurrent disease. GTD is a highly curable disease. Women with hydatidiform mole have an excellent prognosis and rarely need treatment, while women with GTN also have a very good prognosis but require treatment.
What is gestational trophoblastic disease?
Gestational trophoblastic disease (GTD) is a group of rare diseases in which abnormal trophoblast cells grow inside the uterus after conception. In gestational trophoblastic disease (GTD), a tumor develops inside the uterus from tissue that forms after conception (the joining of sperm and egg).
What are other names for gestational trophoblastic disease?
Gestational trophoblastic disease (GTD) may also be called gestational trophoblastic tumour (GTT). Hydatidiform mole (one type of GTD) may also be called molar pregnancy.
What happens if you have gestational trophoblastic disease?
In GTD, there are abnormal changes in the trophoblast cells that cause tumors to develop. Most GTD tumors are benign (noncancerous), but some have the potential to turn malignant (cancerous).
What is the cause of gestational trophoblastic disease?
Causes of Gestational Trophoblastic Disease The most common types of gestational trophoblastic disease occur when a sperm cell fertilizes an empty egg cell or when two sperm cells fertilize a normal egg cell. Your risk is higher based on your: Age: Gestational trophoblastic disease occurs in women of childbearing age.
What do you need to know about gestational trophoblastic disease?
1 Gestational trophoblastic disease is the name given to a group of tumors that form during abnormal pregnancies. 2 GTD is rare, affecting about one in every 1,000 pregnant women in the U.S. 3 While some GTD tumors are malignant (cancerous) or have the potential to turn cancerous, the majority are benign (noncancerous).
How are the trophoblast cells affected in GTD?
The trophoblast helps the embryo implant itself to the uterine wall. These cells also form a large part of the tissue that make up the placenta — the organ that supplies nutrients to a developing fetus. In GTD, there are abnormal changes in the trophoblast cells that cause tumors to develop.
Where does a placental-site trophoblastic tumor ( pstt ) form?
Placental-site trophoblastic tumors. A placental-site trophoblastic tumor (PSTT) is a rare type of gestational trophoblastic neoplasia that forms where the placenta attaches to the uterus. The tumor forms from trophoblast cells and spreads into the muscle of the uterus and into blood vessels. It may also spread to the lungs, pelvis, or lymph nodes.
When do you find out if you have a trophoblastic tumor?
Placental-site trophoblastic tumor: This extremely rare, slow-growing tumor develops where the placenta attaches to the uterine wall. Placental-site trophoblastic tumors are often not discovered until years after a full-term pregnancy.