Who is most likely to be a cystic fibrosis carrier?

Who is most likely to be a cystic fibrosis carrier?

Someone with one normal CF gene and one faulty CF gene is known as a cystic fibrosis carrier….Following are estimates of the CF gene mutation carriers in the United States by ethnicity:

• White people: one in 29.
• Hispanics: one in 46.
• Black people: one in 65.
• Asian Americans: one in 90.

What percentage of Americans are carriers for cystic fibrosis?

It is estimated that approximately 1 in 35 Americans is a carrier of the CFTR gene mutation, which means more than 10 million Americans are cystic fibrosis carriers.

What percentage of the Caucasian population would be carriers for cystic fibrosis?

Cystic fibrosis is most common among Caucasians. In the U.S., the chances of being a carrier of a CFTR mutation are: 1 in 29 Caucasian-Americans. 1 in 46 Hispanic-Americans.

How common is cystic fibrosis in Africa?

Cystic fibrosis (CF) is a common autosomal recessive disorder in populations of European descent. However, very little is known about CF in populations of African origin among whom it has been believed to be extremely rare.

How did I become a CF carrier?

To have cystic fibrosis, a child must inherit one copy of the cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation from each parent. People who have only one copy of a CFTR gene mutation do not have CF. They are called “CF carriers.”

Can you have symptoms of CF as a carrier?

CF carriers do not experience any symptoms. As a result, most people who are carriers remain unaware that they have the CF gene. A person may only find this out if they receive a positive result from a carrier test or have a child with CF.

What ethnicity is most likely to get cystic fibrosis?

The cystic fibrosis gene is most common in Caucasians of northern European descent. The disease occurs most frequently in these people, but can occur in any ethnic population. Parents can be tested to see if they are carriers; however, it’s not possible to identify every person who carries a gene for cystic fibrosis.

What if only one parent is a CF carrier?

If only one of you is found to be a carrier, the chance that you will have a child with CF is very low, although not completely eliminated. If you are both carriers, each pregnancy will have a 1 in 4, or 25 percent chance of being affected with cystic fibrosis.

How many people have cystic fibrosis in South Africa?

“How well or sick children with cystic fibrosis are depends partly on how early or late they are diagnosed,” Zampoli explained. “Generally, the sooner cystic fibrosis is diagnosed, the better the long-term prognosis.” As things stand, the disease affects some 520 adults and children in South Africa.

Does cystic fibrosis affect a certain ethnic group?

Cystic fibrosis is a common genetic disease within the white population in the United States. The disease occurs in 1 in 2,500 to 3,500 white newborns. Cystic fibrosis is less common in other ethnic groups, affecting about 1 in 17,000 African Americans and 1 in 31,000 Asian Americans.

How much does CF carrier test cost?

The CF carrier test costs about $200 – $300 per person. You need to check with your own insurance company to see if they will pay.

Can you be a carrier of cystic fibrosis without family history?

Cystic fibrois is caused by an altered gene that a person inherits from his or her parents. CF is inherited in a recessive manner, which means both parents must be carriers to have an affected child. A person who has no family history of CF and no children with CF can still be a CF carrier.

How often does cystic fibrosis occur in African Americans?

How common is cystic fibrosis? Cystic fibrosis is one of the most common genetic disorders in white people in the United States, occurring in one of every 3,200 live births. It is less common in African Americans (1 in 17,000), Asian Americans (1 in 31,000) and Native Americans.

How many African Americans are carriers of CF?

A CFTR mutation, 3120+1G→A, which was first reported in three African-American CF patients, has been shown to account for 9-14% of African-American CF chromosomes. It has also been found in 4/6 CF chromosomes in South African blacks and one CF chromosome of Cameroonian origin.

What are the chances of getting cystic fibrosis?

In the U.S., the chances of being a carrier of a CFTR mutation are: 1 1 in 29 Caucasian-Americans 2 1 in 46 Hispanic-Americans 3 1 in 65 African-Americans 4 1 in 90 Asian-Americans

How are cystic fibrosis mutations identified in the African diaspora?

Cystic fibrosis mutations identified in the African Diaspora Definition of abbreviation: U = unknown mutation. Genzyme87 refers to a commercially available panel. In the publication that used this panel ( 17 ), the individual mutation frequencies were not reported. *These mutations have no associated functional study.