What is the function of gamma globulin?

What is the function of gamma globulin?

n. A protein fraction of blood serum containing many antibodies that protect against bacterial and viral infectious diseases. A solution of gamma globulin prepared from human blood and administered for passive immunization against measles, German measles, hepatitis A, poliomyelitis, and other infections.

What does gamma globulin protect against?

From the studies reviewed it is apparent that gamma globulin is of value in preventing hepatitis both when administered as mass prophylaxis in an epidemic, and when given to persons in close contact with a person who has the disease.

What is a Gammagoblin shot for?

When an individual is not immune to measles and then exposed to the virus, Ig is given to those who are unable to receive the measles, mumps, rubella (MMR) vaccine.

Why is gamma globulin important?

Gamma globulin injections are usually given in an attempt to temporarily boost a patient’s immunity against disease. Injections are most commonly used on patients having been exposed to hepatitis A or measles, or to make a kidney donor and a recipient compatible regardless of blood type or tissue match.

What causes increased gamma globulin?

Increased gamma globulin proteins may indicate: Blood cancers, including multiple myeloma, Waldenström macroglobulinemia , lymphomas, and chronic lymphocytic leukemias. Chronic inflammatory disease (for example, rheumatoid arthritis ) Acute infection.

What causes gamma globulin deficiency?

The most common cause is common variable immunodeficiency (CVID). Causes of secondary hypogammaglobulinemia include gastrointestinal losses (e.g., malabsorption/protein-losing enteropathy), nephrotic syndrome, hematologic malignancy, and medication (e.g., immunosuppressives, such as corticosteroids and chemotherapy).

How long does gamma globulin last?

This will usually range from 1-2 g/kg as a single dose. The pharmacokinetic properties of IVIG in healthy persons are well defined and last approximately 22 days; however, in persons with certain illnesses, they can last as few as 6 days.

Where is gamma globulin injected?

This medicine is for injection into a muscle or infusion into a vein or skin. It is usually given by a health care professional in a hospital or clinic setting.

Are gamma globulin shots painful?

Muscle stiffness, redness, warmth, pain, and tenderness at the injection site may occur. Fever, chills, headache, and joint pain may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

What if gamma globulin is high?

High levels may indicate infection, inflammatory disease or immune disorders. High globulin levels may also indicate certain types of cancer, such as multiple myeloma, Hodgkin’s disease, or malignant lymphoma.

What does it mean if my IgG is high?

High levels of IgG may mean a long-term (chronic) infection, such as HIV, is present. Levels of IgG also get higher in IgG multiple myeloma, long-term hepatitis, and multiple sclerosis (MS).

Wie hoch sind die Gammaglobuline im Blut?

Die Gammaglobuline machen ca. 9 – 16% der Plasmaproteine aus, entsprechend 6 – 11 g/l. Liegen sie im Blut in erhöhter Konzentration vor, spricht man von einer Hypergammaglobulinämie, im umgekehrten Fall von einer Hypogammaglobulinämie. Eine pathologische Verteilung der Gammaglobuline wird als Dysgammaglobulinämie bezeichnet.

Wie hoch ist der Gamma-GT-Wert für Kinder?

Dabei ist die Höhe des Gamma-GT-Wertes proportional zum Umfang der Leberschädigung und damit ein Hinweis für die Schwere der Erkrankung: Je höher der Gamma-GT-Wert, desto größer der Schaden! In der folgenden Tabelle finden Sie die Gamma-GT-Referenzwerte für Kinder verschiedener Altersstufen sowie für Frauen und Männer (Messung bei 37°C):

Wie kann man die Gamma-GT-Blutwerte überprüfen?

Bei bereits bekanntem Alkoholismus kann der Laborwert zur Überprüfung der Abstinenz während einer Entzugstherapie herangezogen werden. Patienten, die seltene Alkoholexzesse erleben, haben allerdings keinen veränderten GGT-Spiegel. Die Gamma-GT-Blutwerte sind abhängig von Alter und Geschlecht.

Ist eine erhöhte Gamma-GT eine Erkrankung?

Eine erhöhte Gamma-GT allein genügt noch nicht, um eine bestimmte Erkrankung festzustellen. Häufig sind im Rahmen der Diagnostik bereits andere Laborwerte bestimmt worden, die weitere Hinweise auf die Ursache liefern, zum Beispiel ALT, AST oder Cholestaseparameter.