What is Bullosis diabeticorum?

What is Bullosis diabeticorum?

Bullous diabeticorum is a rare cutaneous complication of diabetes mellitus (DM). It is a spontaneous, non inflammatory, blistering condition usually found in long-standing diabetic patients with poor glycemic control. [1] It can mimic other vesicobullous disorders, and is often underdiagnosed.

What causes Bullosis diabeticorum?

The etiology of bullous disease of diabetes (bullosis diabeticorum) is unknown. Prominent acral accentuation of bullous disease of diabetes lesions suggests a susceptibility to microtrauma-induced changes. However, most of the patients developed blister spontaneously without history of trauma.

How is bullous diabeticorum treated?

Drug therapy (ie, antibiotics) is only warranted when secondary staphylococcal infection is present. For recurrent lower limb bullous diabeticorum, successful treatment with autologous bone marrow mesenchymal cell transplantation therapy has been reported.

What is diabetic Cheiropathy?

Diabetic stiff hand syndromen, also known as diabetic cheiroarthropathy, is a disorder in which finger movement becomes limited as the hands become waxy and thickened.

Is granuloma annulare related to diabetes?

Granuloma annulare (GA) is usually a self-limited, benign granulomatous disease of the dermis and subcutaneous tissue. It’s generalized or disseminated form is associated with underlying diabetes mellitus and at times it precedes the sign and symptoms of diabetes mellitus.

Can high blood sugar cause blisters?

Diabetic blisters are rare and more common in people with uncontrolled blood glucose than in others with the condition. In most cases, the blisters are painless and will heal on their own within a few weeks.

Can too much sugar cause blisters?

How do diabetic sores start?

How Do Diabetic Foot Ulcers Form? Ulcers form due to a combination of factors, such as lack of feeling in the foot, poor circulation, foot deformities, irritation (such as friction or pressure), and trauma, as well as duration of diabetes.

What are water blisters caused from?

A friction blister (“water blister”) is a collection of clear, colorless fluid trapped between or beneath the top layer of skin, the epidermis. Water blisters typically form when skin rubs against a surface, causing friction. Burns, frostbite or infections can also cause water blisters.

How do you treat diabetic fingers?

6 Tips for Healing Bruised Fingers

  1. Change Your Lancet Often. Although many people may reuse their lancets, they are likely to become dull over time, causing more pain with prolonged use.
  2. Wash Your Hands Before Testing.
  3. Choose A Less Painful Site.
  4. Prepare Your Site.
  5. Rotate Sites.
  6. Stop the Blood Flow.

What to know about bullosis diabeticorum workup?

Bullous Disease of Diabetes (Bullosis Diabeticorum) Workup 1 Approach Considerations. The clinical workup of bullous disease of diabetes (bullosis diabeticorum) is fairly straightforward. 2 Immunofluorescence. No primary immunologic abnormality is noted in bullous disease of diabetes. 3 Skin Biopsy and Histologic Findings.

How does bullous disease of diabetes affect caterpillars?

Dermal changes (eg, capillary wall thickening, dermal sclerosis) may reflect the patient’s underlying diabetes mellitus (see the image below). Caterpillar bodies typical of porphyria have been reported in lesions of bullous disease of diabetes.

What can be done about bullous diabeticorum blisters?

Most blisters heal with wound care and off-loading without complications. There are reports of secondary infection. Bullosis diabeticorum can precede the development of underlying neuropathic ulceration. Table 1 Treatment options are outlined in the Table.

Where does bullous disease of diabetes usually occur?

Bullous disease of diabetes (bullosis diabeticorum) blisters occur spontaneously and abruptly, often overnight, and usually without known antecedent trauma. Most frequently, it is observed as a unilateral lesion involving the foot or leg, although bilateral lesions as well as multiple lesions have been reported;