What are the levels of dysplasia?
There are 3 levels: CIN I (mild dysplasia) CIN II (moderate to marked dysplasia) CIN III (severe dysplasia to carcinoma in situ)
How does cervical dysplasia progress?
These abnormal cells are called lesions. Cervical dysplasia lesions can regress (which means they shrink and may even disappear), persist (the lesions remain present but don’t change), or progress to become a high-grade lesion or cervical cancer. Cervical cancer is an abnormal growth of the cells of the cervix.
What is the most common site where cervical dysplasia begins?
Cervical cancer begins in the cells of the cervix. Cervical cancer is a type of cancer that occurs in the cells of the cervix — the lower part of the uterus that connects to the vagina. Various strains of the human papillomavirus (HPV), a sexually transmitted infection, play a role in causing most cervical cancer.
Can you have cervical dysplasia without HPV?
Even though HPV infection appears to be necessary for the development of cervical dysplasia and cancer, not all women who have HPV infection develop dysplasia or cancer of the cervix. Additional, yet uncharacterized, factors must also be important in causing cervical dysplasia and cancer.
Can you get cervical dysplasia without HPV?
How often does cervical dysplasia come back?
After treatment for cell changes: about 9 in 10 (90%) people will not have further problems. fewer than 2 in 10 (between 5% and 15%) people may have cell changes that come back.
Which is the most common cause of cervical dysplasia?
In this area, squamous metaplasia is causing squamous cells to replace columnar cells. This cell growth and change can allow the entrance of human papillomavirus (HPV), the cause of more than 90% of cervical cancer. The Pap smear is a sample of cells from this area to screen a patient for abnormalities such as cervical dysplasia.
When to use ablation or cryotherapy for cervical dysplasia?
If no risk factor present (adequate colposcopy, ECC ≤ CIN1, etc), treatment can be confined to the T-zone with either ablation (cryotherapy, laser) or excision (LEEP). a) If excisional margins ≥ CIN2 see 4a2 above. b) If excisional margin < CIN 2 or ablation done, see 4a3 above.
When to treat cin1 after a cervical biopsy?
c. If CIN1 reported on ECC, management depends upon initial cytology and biopsy results: If initial cytology not ASC-H or > HSIL, may manage as CIN1 on biopsy, but include repeat ECC at 12 months (unless pregnant). If initial cytology ASC-H or HSIL or if biopsy > CIN2, treat for specific abnormality.